Novo Nordisk enters the Super Bowl spotlight for the first time this year with a Big Game commercial introducing Americans to the FDA-approved Wegovy pill, the first and only oral GLP-1 medication for weight loss. The campaign, titled “A New Way to Wegovy,” uses humor and familiar faces to challenge stigma around obesity treatment and reframe weight management as a medical conversation rather than a moral one.
Airing during Super Bowl LX, the spot features Kenan Thompson, DJ Khaled, Danielle Brooks, Ana Gasteyer, John C. Reilly, and Danny Trejo, inviting viewers to rethink long-held assumptions about how people approach weight loss. Wegovy pill is prescribed alongside a reduced-calorie diet and increased physical activity for adults with obesity, or overweight adults with related medical conditions, to help them lose weight and keep it off. Watch below:
“Millions of people are curious about weight-management medicine but are waiting for an option that works for them,” said Ed Cinca, senior vice president of Marketing and Patient Solutions at Novo Nordisk. “Wegovy pill brings a once-daily, clinically proven option backed by science, and the Super Bowl gives us a rare opportunity to start an honest, stigma-free conversation at scale.”
DJ Khaled echoed that message in the campaign, noting that even with discipline and consistency, results are not always guaranteed. He said the medication offers an option for people who are putting in the work but still not seeing the outcomes they want.
Wegovy pill is now broadly available through more than 70,000 U.S. pharmacies, including CVS and Costco, as well as select telehealth providers such as Ro, LifeMD, and Weight Watchers. With a prescription, the starting dose is available through a self-pay offer for $149 per month, with additional savings available for eligible insured patients.
CREDITS:
BRAND: Novo Nordisk
AGENCY: M+C Saatchi North America
- Chief Creative Officer: Laurence Thomson
- Chief Creative Officer: Rob Doubal
- Chief Creative Officer: Stevie Archer
- Creative Director: Steve McElligott
- Creative Director: Jerome Marucci
- Creative Director: Scott Kaplan
- Creative Director: Vlad Ivangorodsky
- Managing Director: John Swartz
- Managing Director: Amy Frisch
- Managing Director: Alex Osorio
- Chief Strategy Officer: Chris Turney
- Strategy Director: Nick Petrillo
- Executive Producer: Tennille Teague
- Head of Production: Christopher McLallen
- Group Account Director: Ronni Chow
- Group Account Director: Emma Delorm
- Account Supervisor: Caitlin Braudis
- Account Supervisor: Tommy Gerity
- Account Executive: Elyse Rice
- Project Manager: Joi Wu
PRODUCTION COMPANY: O Positive
- Director: Kenny Herzog
- Executive Producer: Ralph Laucella
- Executive Producer: Marc Grill
- Executive Producer: Ken Licata Jr.
- Director of Photography: Jonathan Freeman
POST PRODUCTION: Rare Medium TV
- Producer: Nubia Lima
- Colorist: Fergus McCall
VFX COMPANY: Parliament
- VFX Supervisor: James Mulholland
- Creative: Taner Besen
- Creative: Dan Fine
- Creative: Adam Deutsch
- Creative: Ashley Thomas
- Creative: Edgar De La Torre
- Creative: James Cudahy
- Creative: Ryan Harper
- Creative: Sabrina Chan
- Post Production: Kat Maidment
- Post Production: Olivia Schneider
- Post Production: Sarah Woods
- Post Production: Kate Matos
EDIT: Mackcut
- Executive Producer: Gina Pagano
- Editor: Ian McKenzie
- Editor: Zach Gentry
MUSIC & SOUND: M+C Saatchi North America
Music Producer: Patrick Oliver
MUSIC & SOUND: Heard City
- Executive Producer: Nick Duvarney
- Sound Designer: Phil Loeb
- Sound Engineer: Jeremy Siegel
MUSIC & SOUND: The Elements Music
- Licensing: Nick Maker
- Licensing: Emily Weinstein
- Music Editing: Dan Bewick
- Music Editing: Scott Coleman
- Sound Producer: Danielle Beauvoir
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